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Learner Reviews & Feedback for Design and Interpretation of Clinical Trials by Johns Hopkins University

4.7
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4,330 ratings

About the Course

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

Top reviews

NP

Oct 3, 2016

The powerpoints and audio lectures are very clear and concise, much appreciated. I would also appreciate more exercises or reading materials, to help solidify our understanding of the topics.

VV

Nov 18, 2020

Good course overall. Some information was complex and the slides were not always complete. I personally found the first 2-3 quizzes quite difficult. However, the course is useful and interesting.

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526 - 550 of 727 Reviews for Design and Interpretation of Clinical Trials

By Faiza M

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Sep 11, 2023

QUITE DETAILED

By hasan a

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Apr 26, 2023

Best course...

By SOURAV D

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Oct 12, 2022

goooooooooood

By Aneeq S

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Sep 2, 2022

Really helpful

By Anna K

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May 3, 2022

a great course

By Ana R A

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Apr 13, 2021

really helpful

By shimaa m n

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Jun 7, 2020

Perfect course

By Miriam C V F

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Apr 7, 2020

Really useful!

By Christopher H

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Dec 30, 2019

Learned a lot!

By Tereza F

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Apr 3, 2016

nicely done :)

By Sarah A

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Oct 23, 2020

Great course!

By Chen W C

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Jun 19, 2019

Nice lecture!

By Cansu d M

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May 3, 2018

Great course.

By Jyoti G

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Aug 24, 2017

Superb course

By Alma D

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Jun 7, 2016

Great course!

By Surabhi M M

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Jan 18, 2023

10 out of 10

By Luping Y

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May 29, 2022

Reat course!

By Tran T T T

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Nov 14, 2021

great topic

By Ikartini A

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Nov 19, 2020

Good course!

By Phob G

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Oct 20, 2020

Great course

By Karthikeyan P

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Aug 1, 2020

Great Course

By Amer M A S

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Mar 7, 2020

Recommended!

By Oluwatobi A

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Feb 5, 2020

great course

By Sakis P

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Jan 16, 2020

great course