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Learner Reviews & Feedback for Introduction to Systems Biology by Icahn School of Medicine at Mount Sinai

4.2
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560 ratings

About the Course

This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems? The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses....

Top reviews

AM

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Coursera make it different...

I'm pretty lucky to find a systems biology course like this.

MS

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Module 1: Introduction was a challenge. The lecture verbal dialogue needs to be edited in the corresponding "printed" version.

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101 - 116 of 116 Reviews for Introduction to Systems Biology

By Alejandro V (

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May 29, 2017

Great new area to explore and study, however some subjects were not explained adequately.

By James H

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Jun 20, 2024

Challenging for someone not trained in the biological sciences, but still possible.

By Le X H

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Aug 5, 2024

The topic is helful for beginer into new field of study like me

By Md. M H

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Feb 26, 2016

Very very informative course for the beginners like me!

By Jiho C

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Mar 9, 2017

Good lecture, but not systematic curriculum

By Mariya P

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Nov 25, 2019

Instructor is very hard to engage with.

By Amir B

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Jan 1, 2016

a bit to hard for an introduction cours

By Arpita R

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Aug 2, 2022

Excellent course work!

By Kang c

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Jun 14, 2016

A very useful course!

By Chalasani S S N

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Apr 10, 2019

useful

By Tom S

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Jan 24, 2023

some subjects are mentioned without enough explanation. It seems that the goal is to understand the big picture but sometimes hard to follow without understand the micro details.

By Karl D

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Jul 26, 2017

Good overview of systems biology, but the graded tests are somewhat difficult to understand for someone without a biology background such as myself.

By Connie N

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Oct 1, 2020

Really interesting content, but could use a rework on formatting, style, and clarity.

By Alan R d F K M

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Jan 20, 2020

Could give more basic information about systems theory

By Milena J

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Feb 12, 2016

The lectures were somehow chaotic.

By Mainak B

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Feb 23, 2020

Tough and brain storming